Late Show with David Letterman Season 13 Episode 51 George Clooney, Ashlee Simpson ( Air Date 2005-11-21 ) Genre Talk, Comedy category. Overview "Dave shocks the audience with the news that Oprah Winfrey will be a guest on the show a week from Thursday; Biff undergoes Lasek eye surgery; George Clooney promotes "Syriana."".

Late Show with David Letterman Season 13 Episode 51 George Clooney, Ashlee Simpson

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Watch: Late Show with David Letterman Season 13 Episode 51 George Clooney, Ashlee Simpson on CWR-CRB
Stars: David Letterman, Paul Shaffer, Alan Kalter
Director: David Letterman

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